Hepatoxic Drugs
👊🏻 Drug-induced liver injury 🥊
💊 There are SO many medications that can cause liver injury through various mechanisms. However, some key medications have black box warnings for liver toxicity and are more well-known for their risk. These are the ones that you should know for exams! 🗒️
🔺 Hepatoxic drugs are usually well tolerated unless high doses are administered. In most cases, the primary treatment is to STOP the drug, especially when liver enzymes (AST and ALT) rise 3 times above their upper limit of normal.
🧠 Some other helpful memory tips:
-Acetaminophen’s brand name is Tylenol which looks similar to ‘Tired Liver’.
-Nefazodone and Nevirapine are never used anymore due to their severe liver toxicity so think never-zodone and never-apine.
-KEToconazole can KILL your liver
🤔Some of them are a stretch but if you’re willing to try them out and they help you retain the information then that’s a win in my books. ✌🏻