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Clindamycin

Antibiotic Renal Dosing

Antibiotics are commonly used to treat infections. When considering what dose to prescribe to a patient, it is important to evaluate the patient’s renal function as many antibiotics are excreted by the kidney.⁠ ⁠ It is recommended to study the list of antibiotics that do NOT require renal dose adjustments rather than a list of the ones that do (as it can get very long and overwhelming). ⁠

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Antibiotics that Cover MRSA

Methicillin-resistant Staphylococcus aureus (MRSA) is an infection caused by Staphylococcus (staph) bacteria that has an oxacillin minimum inhibitory concentration (MIC) of greater than or equal to 4 micrograms/mL. ⁠ ⁠ ⭐ MRSA infection is one of the leading causes of hospital-acquired infections and is commonly associated with significant morbidity, mortality, length of stay, and cost burden. ⁠ ⁠ ⭐ MRSA infections can be further divided into hospital-associated (HA-MRSA) infections and community-associated (CA-MRSA) infections. They differ not only in respect to their clinical features and molecular biology but also to their antibiotic susceptibility and treatment⁠

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Antibiotics that cover anaerobes

Anaerobic bacteria are bacteria that do not live or grow when oxygen is present. In humans, these bacteria are most commonly found in the gastrointestinal tract. ⁠ ⁠ 🔺 They play a role in conditions such as appendicitis, diverticulitis, and perforation of the bowel so it is important to make sure we have adequate anaerobic coverage when empirically treating these infections. ⁠ ⁠ 💊 There are several antibiotics that cover anaerobes in addition to other bacteria. ⁠

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