CYP450 Enzymes, Major Inducers of

๐Ÿ‘‰๐Ÿป Drugs that are inducers increase CYP450 enzyme activity by increasing enzyme synthesis. โ  โ  ๐Ÿ‘‰๐Ÿป A drug also may be metabolized by the same CYP450 enzyme that it induces. Carbamazepine (Tegretol), a potent enzyme inducer, must be initiated at a low dose and then increased at weekly intervals as its half-life gradually decreases over time.โ 

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