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ACE inhibitors

ACE inhibitors vs. ARBs.

                                                               What’s the difference?⁠

💊Angiotensin converting enzymes (ACE) inhibitors and angiotensin receptor blockers (ARBs) are antihypertensive medications used to treat high blood pressure and other comorbid conditions.⁠

💊While the enzyme inhibitors work by reducing the level of angiotensin II in the body, the receptor blockers inhibit the function of angiotensin II by directly blocking the specific receptor. ⁠

⭐️Key Takeaways⭐️⁠

-ACE inhibitors and ARBs have similar benefits, and both work equally well in the body though ARBs are thought to have less side effects. ⁠
-ACE inhibitors and ARBs are both considered first line for the treatment of hypertension. ⁠
-ACE inhibitors remain first line for HFrEF with ARBs as an alternative. ⁠
-For those who cannot tolerate an ACE inhibitor, ARBs are reasonable substitutes (ex: dry cough)⁠
-It is NOT recommended to treat hypertension patients with both ACE inhibitor and ARB as it can increase adverse effects. ⁠

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ACE-inhibitors ⁠

 Let’s talk about ACE-inhibitors ⁠⠀
⁠⠀
💊 Angiotensin-converting enzyme (ACE) inhibitors are a class of drugs mainly used in the treatment of hypertension and heart failure with reduced ejection fraction (HFrEF). They are one of the top 200 drugs prescribed and because of that, they are an important class to know. ⁠⠀
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⭐ Drugs in this class end in the suffix ‘-pril’ such as: ⁠⠀
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-LisinoPRIL⁠⠀
-FosinoPRIL⁠⠀
-EnalaPRIL⁠⠀
-RamiPRIL⁠
-QuinaPRIL⁠
-BenazePRIL⁠⠀
⁠⠀
❗Do not use this medication in patients who: ⁠⠀
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-Have a hypersensitivity to ACE inhibitors or any of their components⁠⠀
-Pregnant or breastfeeding: box warning for patients who are or may become pregnant as it can cause fetal toxicity⁠⠀
-History of angioedema, bilateral renal stenosis, and concurrent use with aliskiren in patients with diabetes⁠⠀
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